COLUMBUS, Ohio — Kenny Guiton took over when Braxton Miller left with a sprained left knee, running for one touchdown and passing for two while leading No. 3 Ohio State over San Diego State 42-7 on Saturday.
Miller watched the last three quarters from the sideline after being sandwiched between two tacklers on the Buckeyes’ seventh offensive play. The Buckeyes (2-0) didn’t need him.
Guiton, who helped save Ohio State’s 12-0 season a year ago, had the most playing time he’s ever had in a game. He set career bests with 19 of 28 passing for 152 yards and 83 rushing yards.
It was another disappointing outing for the Aztecs (0-2), who lost 40-19 to FCS Eastern Illinois at home in their opener.
Guiton came in having completed 14 of 25 passes for 144 yards and two touchdowns with two interceptions in his 16 career games. He had totaled 59 yards rushing on 14 attempts.
No. 19 Northwestern 48, Syracuse 27
EVANSTON, Ill. — Trevor Siemian threw for 259 yards and a career-high three touchdowns, Kain Colter passed for a touchdown and ran for one, and No. 19 Northwestern pounded Syracuse.
Tony Jones added a personal-best 185 yards receiving and a 47-yard TD, and the Wildcats (2-0) racked up 581 yards in all. They also intercepted Syracuse’s Drew Allen four times on the way to an easy victory.
They scored the game’s first 20 points and led 34-7 at the half after collecting 387 yards, with their quarterbacks picking apart Syracuse (0-2).
They each completed 11 of 12 passes in the first half, and Colter seemed to be fine after suffering a concussion early in last week’s win at California.
He was 15 of 18 for 116 yards and ran for 87 yards.
No. 21 Wisconsin 48, Tennessee Tech 0
MADISON, Wis. — Melvin Gordon ran for 140 yards and a score, and Wisconsin’s overpowering defense got its second straight shutout with a win over FCS school Tennessee Tech.
Joel Stave was 24 of 29 for 219 yards with three touchdowns and an interception, while defensive back Darius Hillary set the tone early by forcing a fumble that set up a score for the Badgers (2-0).
The early-season tuneup went about as well as could be expected for first-year coach Gary Andersen, who’s breaking in a new 3-4 defense in Madison. Wisconsin had no problems against the Golden Eagles (1-1), whose spread offense got outmuscled by the bigger Badgers.
Including Gordon, three backs went over 100 yards for the second straight game.
No. 22 Nebraska 56, S. Mississippi 13
LINCOLN, Neb. — Stanley Jean-Baptiste and Ciante Evans returned first-quarter interceptions for touchdowns and Nebraska made quick work of Southern Mississippi in the victory.
Taylor Martinez threw for three touchdowns and Ameer Abdullah ran for two more for the Cornhuskers (2-0), who now turn their attention to next week’s home game against No. 18 UCLA.
Jean-Baptiste jumped in front of Rickey Bradley Jr. just as Allan Bridgford’s pass arrived on the third play of the game and ran it back 43 yards. Evans put the Huskers up 21-3 with the first of his two interceptions, catching a ball tipped by Tyre’oune Holmes and going 22 yards to the end zone.
Indiana 41, Navy 35
BLOOMINGTON, Ind. — Keenan Reynolds rushed for 127 yards and three touchdowns, leading Navy to a season-opening victory.
The Midshipmen (1-0) played almost flawlessly, finishing with 444 yards rushing, no turnovers, five penalties and only three carries for negative yards.
Navy has now won 20 games over BCS foes since 2003 — the most of any non-BCS school in the nation during that span.
For Indiana (1-1), it was a huge deflation after a 73-35 victory over Indiana State.
But as the Hoosiers continued to score, the defense was confounded by Navy’s ground game and never even forced a punt.
Navy scored on its first three possessions, taking a 17-0 lead. Reynolds scored on runs of 1, 2 and 1 yard as the Midshipmen fended off Indiana’s rallies.
Illinois 45, Cincinnati 17
CHAMPAIGN, Ill. — Nathan Scheelhaase passed for 312 yards and four touchdowns to lead Illinois to a surprise win.
The Illini (2-0) went up 21-0 in the second quarter and survived a Bearcat rally to stay undefeated.
For the Bearcats (1-1) the loss was made worse by quarterback Munchie Legaux’s injury. He left in the fourth quarter on a cart with what appeared to be a serious leg injury. Details were not immediately available.
Scheelhaase threw to 11 different receivers. The biggest catch was Steve Hull’s 22-yard touchdown late in the third quarter. It capped a 99-yard drive and put Illinois up 28-10.
Purdue 20, Indiana State 14
WEST LAFAYETTE, Ind. — Ricardo Allen’s interception with 19 seconds remaining preserved Purdue’s win.
Indiana State (0-2) reached the Purdue 36-yard line in the final minute before Allen stepped in front of Mike Perish’s pass and gave Darrell Hazell his first win as Purdue’s coach.
Akeem Hunt returned a kickoff 90 yards for a touchdown and ran for 82 yards on 22 carries for the Boilermakers (1-1).
Perish passed for 284 yards and two touchdowns for Indiana State, an FCS team that lost to Indiana 73-35 the previous week.
Iowa 28, Missouri State 14
IOWA CITY, Iowa — Jake Rudock and Mark Weisman each ran for a pair of touchdowns and Iowa beat Missouri State, snapping a seven-game losing streak dating back to 2012.
Weisman had 180 yards rushing for the Hawkeyes (1-1), who prevailed despite a somewhat shaky performance against an FCS opponent.
Weisman scored on runs of 10 and 3 yards to help the Hawkeyes take a 21-0 lead late in the third quarter. Missouri State answered with touchdowns on back-to-back plays from scrimmage early in the fourth quarter, pulling within 21-14 with 14:15 to go.
Michigan St. 21, South Florida 6
EAST LANSING, Mich. — Shilique Calhoun scored on a fumble return and an interception return, enabling Michigan State to overcome another poor offensive performance in a victory over South Florida.
The Spartans (2-0) rotated Connor Cook, Tyler O’Connor and Andrew Maxwell at quarterback, but their offense contributed only one touchdown. The defense has scored four of Michigan State’s six TDs this season.