PHILADELPHIA at PITTSBURGH
OPENING LINE: Steelers by 4
SERIES RECORD: Eagles lead 47-27-3
LAST MEETING: Eagles beat Steelers 15-6, Sept. 21, 2008
LAST WEEK: Eagles beat Giants 19-17; Steelers had bye
DID YOU KNOW? Steelers haven't lost back-to-back games since 2009, coming off 34-31 loss to Oakland two weeks ago ... Steelers have started season 6-2 in each of coach Mike Tomlin's first five seasons ... Pittsburgh leads NFL in time of possession, averaging more than 35 minutes a game ... Steelers QB Ben Roethlisberger second in NFL in quarterback rating at 109.2 ... Pittsburgh is 26-6 in last 32 games against NFC opponents and 4-1 coming off bye week under Tomlin. Pittsburgh has won seven straight home games against NFC teams, last loss 21-14 to Giants in 2008
Philadelphia is 9-3-1 against AFC North under coach Andy Reid, including 2-0 this season ... Philadelphia holding opposing quarterbacks to passer rating of 65.8, third-best in NFL … Philadelphia QB Michael Vick first quarterback in 12 years to lead team to three fourth-quarter comebacks in first four games of season ... Eagles lead NFL in yards per game differential, averaging 417.8 yards while giving up 298.3. .. Eagles haven't allowed punt or kickoff return for touchdown since 2008, longest active streak in league.
CLEVELAND at N.Y. GIANTS
OPENING LINE: Giants by 10 1/2
SERIES RECORD: Browns lead 26-19-2
LAST MEETING: Browns beat Giants 35-14, Oct. 13, 2008
LAST WEEK: Browns lost to Ravens 23-16; Giants lost to Eagles 19-17
DID YOU KNOW? Browns have lost 10 straight games dating to last season. Last win was against Jacksonville Nov. 20. ... Rookie quarterback Brandon Weeden has thrown for at least 300 yards in two of last three games. ... Rookie running back Trent Richardson has run for a touchdown in three straight games. ... Browns have played defending Super Bowl champions in four of last five seasons.
Quarterback Eli Manning has won seven straight vs. AFC foes, and has at least 200 yards passing in 23 consecutive games, second longest streak in NFL history. His 1,320 yards passing is 30 yards shy of league-leader Drew Brees. ......RB Ahmad Bradshaw has 981 yards from scrimmage (722 rushing, 259 receiving) and nine TDs in last 10 games vs. AFC opponents. ... Rookie David Wilson third in NFL, averaging 30.2 yards on kickoff returns. ... WR Victor Cruz leads NFL with 32 receptions. ... Domenik Hixon had six receptions for 114 yards last week, starting for injured Hakeem Nicks. … Fullback Henry Hynoski's father, Henry Sr., played for Browns in 1975.
DENVER at NEW ENGLAND
OPENING LINE: Patriots by 7
SERIES RECORD: Broncos lead 27-18
LAST MEETING: Patriots beat Broncos 45-10, Jan. 14, 2012
LAST WEEK: Broncos beat Raiders 37-6; Patriots beat Bills 52-28
DID YOU KNOW? Patriots have scored at least 41 points in each of last three wins against Broncos and are 3-1 in last four matchups. ... Denver has outscored opponents in fourth quarter by league-high 45 points. New England scored 31 against Buffalo in fourth quarter last Sunday. ... Tom Brady and Peyton Manning meet for 13th time and first since Manning joined Broncos. Brady has won eight of 12 meetings. … Brady tied with Brett Favre for third place with 36 consecutive games with at least one touchdown pass. Only players ahead are Drew Brees and Johnny Unitas, with 47 each.
In last Sunday's win over Oakland, Manning completed 30 of 38 passes for 338 yards, three touchdowns and no interceptions: and wasn't sacked. ... Denver 5-2 in last seven games at New England. ... Dan Koppen expected to start at center for Broncos after eight seasons as Patriots starting center. ... Willis McGahee leads active NFL players with 32 games of at least 100 yards rushing. He ran for 112 against Raiders. ... Denver's Eric Decker has 24 catches and Demaryius Thomas 21, tying for second in receptions by teammates this season. The Patriots are first with Wes Welker and Brandon Lloyd catching 25 passes each.
SAN DIEGO at NEW ORLEANS
OPENING LINE: Saints by 3
SERIES RECORD: Chargers lead 7-3
LAST MEETING: Saints beat Chargers 37-32, Oct. 26, 2008
LAST WEEK: Chargers beat Chiefs 37-20; Saints lost to Packers 28-27
DID YOU KNOW? Teams' last meeting came in Wembley Stadium in London. ... Chargers are 2-0 on road. ... Chargers QB Philip Rivers replaced Saints' Drew Brees as starter in San Diego in 2006. ... . Rivers passed for 341 yards, three TDs and one INT with a 104.3 rating in only start vs. New Orleans, marking one of only eight career losses when rating 100 or better. ... TE Antonio Gates has 7,907 career yards receiving, and with 74 more yards will surpass Hall of Famers Jackie Smith (7,918) and Ozzie Newsome (7,980) for fourth-most career yards receiving by TE.
Saints seek to avoid first 0-5 start since 1996, when they finished 3-13. ... Brees seeks NFL record 48th straight regular season game with TD pass. He's tied with Hall of Fame QB Johnny Unitas, who had a TD pass in 47 straight from 1956-60. ... Last time Brees did not throw TD pass was Oct. 4, 2009, a 24-10 win over N.Y. Jets. ... Since joining the Saints in 2006, Brees has passed for 29,744 yards. ... Brees has faced Chargers once, passing for 339 yards with three TDs in 37-32 win in 2008.