NEW ENGLAND at BUFFALO
OPENING LINE: Patriots by 3
SERIES RECORD: Patriots lead 62-41-1
LAST MEETING: Patriots beat Bills 49-21, Jan. 1, 2012
LAST WEEK: Patriots lost to Ravens 31-30; Bills beat Browns 24-14
DID YOU KNOW? Last year's meeting at Orchard Park had Bills rallying from 21-0 second-quarter deficit for 34-31 win that ended Patriots 15-game win streak vs. Buffalo. New England has still owned Bills during Bill Belichick-Tom Brady era, having won 21 of past 23 meetings dating to 2000. Patriots lost two straight for only fourth time since 2003, and they're below .500 for first time since opening 2003 season with 31-0 loss at Buffalo. ... With 40,866 yards passing, Brady 57 shy of moving into 11th on NFL list ahead of Kerry Collins. ...
Bills attempting to get off to second straight 3-1 start after opening last season with three wins. ... Questions remain at running back with Fred Jackson (sprained right knee) attempting to return after missing two games and after C.J. Spiller hurt left shoulder at Cleveland. ... Nine sacks in first three games are most for Buffalo since having 11 to open 2006 season. Bills managed four sacks through first six games last season.
SAN FRANCISCO at N.Y. JETS
OPENING LINE: 49ers by 3 1/2
SERIES RECORD: 49ers lead 9-2
LAST MEETING: 49ers beat Jets 24-14, Dec. 7, 2008
LAST WEEK: 49ers lost to Vikings 24-13; Jets beat Dolphins 23-20 OT
DID YOU KNOW?: 49ers 5-1 all-time on road against Jets: but playing at MetLife Stadium for first time. ... San Francisco practiced all week at Youngstown State in eastern Ohio to avoid return trip to West Coast after playing at Minnesota last Sunday. 49ers did same thing last season after win in Cincinnati and then rallied from 20-0 deficit to stun Eagles 24-23 in Philadelphia. ... QB Alex Smith ranks third in NFL with 69.6 completion percentage. Vernon Davis, called best TE in NFL by Jets coach Rex Ryan, tied with Pittsburgh TE Heath Miller for most TD catches in league this season with four.
Game marks Ryan's first against an NFC West team since becoming Jets' coach in 2009. ... Jets playing first game since CB Darrelle Revis was lost for season with torn ligament in left knee, suffered at Miami. 2010 first-round pick Kyle Wilson will replace him. ... To help compensate for loss of Revis, Jets moving RB Joe McKnight to CB: position he hasn't played regularly since high school. ... Last Sunday's OT win marked 11th time in QB Mark Sanchez's career that he has led Jets to fourth-quarter comeback or OT victories: seven coming on road.
NEW ORLEANS at GREEN BAY
OPENING LINE: Packers by 7
SERIES RECORD: Packers lead 15-7
LAST MEETING: Packers beat Saints 42-34, Sept. 8, 2011
DID YOU KNOW? Saints have won three of past five meetings. ... QB Drew Brees has touchdown pass in 46 consecutive games and can tie longest streak in NFL history, held by Hall of Famer Johnny Unitas with 47. ... In four starts vs. Green Bay, Brees has 1,458 yards passing (364.5 per game), 11 TDs and two INTs. Has 300-plus yards and two-plus TDs in all four games. ... In last meeting, Darren Sproles had 250 yards combined with a 72-yard punt return for a TD. Since 2011, Sproles leads NFL RBs with 104 receptions. ... TE Jimmy Graham had a TD in last meeting with Packers and is aiming for TD in seventh game in row. ... Saints offense ranks first in NFC with a 70 percent TD rate in red zone.
RB Cedric Benson rushed for two TDs in last game vs. New Orleans, Dec. 5 2010 with Cincinnati. ... WR Greg Jennings aims for fourth game in row vs. New Orleans with TD. ... ... Packers pass defense leads NFL allowing 125.3 yards per game. Total defense is second in NFC and third in NFL, allowing 261 yards per game. OLB Clay Matthews leads NFL with six sacks. ... Rookie OLB Nick Perry had first career sack last week.
N.Y. GIANTS at PHILADELPHIA
OPENING LINE: Eagles by 2 1/2
SERIES RECORD: Giants lead 82-74-2
LAST MEETING: Eagles beat Giants 17-10, Nov. 20, 2011
LAST WEEK: Giants beat Panthers 36-7; Eagles lost to Cardinals 27-6
DID YOU KNOW? Eagles RB LeSean McCoy renewed rivalry with Giants DE Osi Umenyiora this week, calling him "ballerina in a Giants uniform." ... Eagles have won seven of last eight meetings. ... Giants coach Tom Coughlin 9-11 vs. Eagles, including two playoff losses. ... Giants have forced at least one turnover in 34 of last 36 games. ... K Lawrence Tynes has made franchise-record 166 consecutive extra points since missing one vs. San Francisco on Oct. 21, 2007. ... RB Andre Brown rushed for 113 yards and scored two TDs last week in first NFL start. QB Eli Manning will make 123rd consecutive regular-season start.
Eagles LB Brian Rolle and Giants S Antrel Rolle are cousins. ... QB Michael Vick 3-2 vs. Giants. He's twice rushed for more than 100 yards against them. ... TE Brent Celek has 67 receptions for 996 yards and five TDs in last 14 games. ... Eagles defense has not allowed a TD in the second half, and has held opponents to 2 for 7 in red zone ... P Chas Henry was released despite three 60-plus yard punts in three games. ... Eagles 42-22-1 after loss under coach Andy Reid.
-- The Associated Press